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KMID : 1143420190120472101
Public Health Weekly Report
2019 Volume.12 No. 47 p.2101 ~ p.2110
Marburg Hemorrhagic Fever and Diagnostics
Choi Myung-Min

Park Ok-Kyu
Kang Byung-Hak
Rhie Gi-Eun
Abstract
Marburg hemorrhagic fever is an acute viral hemorrhagic illness caused by the Marburg virus. The first case of laboratory
infection occurred in Germany. However, this disease occurs mainly in the African continent, namely South Africa, Kenya,
Democratic Republic of Congo, Angola and Uganda. Fruit bats are known to be potent natural hosts, but cases of humanhuman contact propagation or laboratory accidents have a direct impact on the incidence of Marburg fever. Because general symptoms are very similar to other hemorrhagic fever diseases, in particular, Ebola, Lassa fever, and malaria, laboratory diagnostic tests are critical. Laboratory diagnostic tests include molecular biological diagnostic tests and serological diagnostic tests, but there are few licensed diagnostic test kits. Nevertheless, laboratory diagnostic tests for the rapid and accurate detection of the Marburg virus play an important role in preparing for the emergence of a public health crisis.
KEYWORD
Marburg virus, Marburg hemorrhagic fever, Diagnostic tests
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